Adverse effects of inhaled corticosteroids.

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Adverse effects of inhaled corticosteroids.

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Adverse effects of inhaled corticosteroids in funded and nonfunded studies.

BACKGROUND Evidence regarding the safety profile of drugs may vary depending on study sponsorship. We aimed to evaluate differences between studies funded by the pharmaceutical manufacturer of the drug (PF) and those with no pharmaceutical funding (NoPF) regarding the finding and interpretation of adverse effects of inhaled corticosteroids. METHODS We assessed the safety reporting of inhaled ...

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Systemic effects of inhaled corticosteroids.

The effectiveness of, and increasing indications for, the use of inhaled corticosteroids in asthma of varying severity prompts important questions to be raised relating to safety and the possibility of adverse systemic steroid effects. This concern is not new and has already resulted in guidelines on the use of spacer devices for high dose inhaled steroids in order to decrease systemic absorpti...

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Psychiatric adverse effects of corticosteroids.

Psychiatric adverse effects during systemic corticosteroid therapy are common. Two large meta-analyses found that severe reactions occurred in nearly 6% of patients, and mild to moderate reactions occurred in about 28%. Although disturbances of mood, cognition, sleep, and behavior as well as frank delirium or even psychosis are possible, the most common adverse effects of short-term corticoster...

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Risk of adverse gastrointestinal events from inhaled corticosteroids.

STUDY OBJECTIVE To determine whether patients prescribed inhaled corticosteroids are at risk for adverse gastrointestinal effects. DESIGN Retrospective cohort study. SETTING Urban health center with an academic affiliation. PATIENTS A total of 19,443 adults (mean age 31.8 yrs) with airways disease, defined as a diagnosis of asthma or chronic obstructive pulmonary disease, and who were pre...

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ژورنال

عنوان ژورنال: BMJ

سال: 1989

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.298.6671.403